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Home Xerostomia (4-9%) Constipation (3-6%) Fatue (2-8%) Libido decrease (3-7%) Anorgasmia (2-6%) Flatulence (2%) Toothache (2%) Weht gain (1%) Menstrual disorder (2%) Neck/shoulder pain (3%) Rhinitis (5%) Flu-like syndrome (5%) Ejaculation disorder (9-14%) Arthralgia Abdominal pain Abnormal bleeding Abnormal dreams Allergy Blurred vision Bronchitis Chest pain Constipation Decreased appetite Decreased concentration Disrupts platelets/hemostasis Dizziness Dyspepsia Fever Heartburn Hot flashes Impotence Irritability Jaw stiffness Lethargy Lhtheadedness Menstrual disorder Hypertension Palpitations Mraine Myalgia Paresthesia Rash Sweating Tinnitus Tremor Urinary frequency Urinary tract infection Verto Vomiting Yawning 65 years Drug is not FDA appored for treatment of bipolar depression In children and young adults, the risks must be wehed against the benefits of taking antidepressants Patients should be monitored closely for changes in behavior, clinical worsening, and suicidal tendencies; this should be done during initial 1-2 months of therapy and dosage adjustments The patient’s family should communicate any abrupt changes in behavior to the health-care provider Worsening behavior and suicidal tendencies that are not part of the presenting symptoms may require discontinuation of therapy This drug is not approved for use in pediatric patients Pregnancy: Conflicting evidence regarding use of SSRIs during pregnancy and increased risk of persistent pulmonary hypertension of the newborn, or PPHN (see Pregnancy) In neonates exposed to SNRIs/SSRIs late in third trimester: risk of complications such as feeding difficulties, irritability, and respiratory problems Caution with seizure disorder, bipolar mania, severe renal impairment; not FDA approved for the treatment of bipolar depression NRIs/SSRIs have been associated with the development of SIADH; hyponatremia has been reported rarely May worsen psychosis in some patients and precipitate a shift to mania or mypomania in patients with bipolar disorder Risk of hyponatremia Risk of mydriasis; may trger angle closure attack in patients with angle closure glaucoma with anatomiy narrow angles without a patent iridectomy Bone fractures are associated with antidepressant therapy; consider the possibility of a fracture in patients with unexplained bone pain, swelling, or bruising Prescriptions should be written for smallest quantity consistent with good patient care and the family or care giver alerted to monitor patient for emergence of suicidality and associated behaviors (anxiety, agitation, panic attacks, insomnia, hostility, akathisia, impulsivity, irritabilty) SSRIs/SNRIs increase risk of abnormal bleeding (further increased if concomitant aspirin, NSAIDs or anticoagulants, or hemorrhagic diathesis) Prolongation of QT interval and ventricular arrhythmias reported, especially in female patients with preexisting QT prolongation or other risk factors Risk of cognitive and motor function impairment; use caution when operating heavy machinery Use with caution in patients with history of seizure disorders or or conditions predisposing to seizures including brain damage and alcoholism May impair platelet aggregation that can result in increased risk of bleeding events including GI bleeding especially if taken concomitantly with aspiring, warfarin, or NSAIDs Risk of serotonin syndrome or neuroleptic malnant syndrome (NMS)-like reactions have been reported with SSRIs alone or with concomitant use of serotonergic drugs, with drugs that impair metabolism of serotonin, or with antipsychotics or other dopamine antagonists No additional benefits at 20 mg/day May cause or exacerbate sexual dysfunction Gradually taper dose before discontinuation; abrupt discontinuation may cause dysphoric mood, dizziness, sensory disturbances, agitation, confusion, anxiety, headache, insomnia, tinnitus, seizures, irritability The above information is provided for general informational and educational purposes only. Lexapro food interactions lexapro isn't working depression lexapro long does take work anxiety lexapro withdrawal 5 mg withdrawal from lexapro and.
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